Diagnostic test deals

As Nemucore advances NMI forward, one thing you need to consider is who else is developing treatments to pursue the AML indication. Additionally, there is one Phase I competitor being developed by Amgen.

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In speaking with Sol Reyna, Ph. Additionally, there has been 3 programs utilizing the Aurora B kinase inhibitor that have ceased development in the past from Astra Zeneca, and Millenium Takeda , which both were discontinued for pipeline re-prioritization. Though there is always a risk that big pharma can leap over small bio-techs the more likely reality is if Nemucore begins to show real progress in clinical trials, one of the organizations will look to acquire it.

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There are several points we want to call out as you consider investment in Nemucore. These are meant only to inform you of some of the risks you take in investing in an early stage bio-tech like Nemucore. In a study performed by the Biotechnology Innovation Organization between and , it was found that only 5. Other notes worth calling out is that Nemucore NMI will most likely be a second line treatment. All of this is to say that the addressable population may ultimately fall to K patients rather than 10 or 20K.

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As we have mentioned above, bio-techs with decent initial clinical trial results can go on to command outsized valuations. This is entirely different world from traditional tech with its own rules. We think with experienced management, a promising drug and companion diagnostic, Nemucore will be a valuable asset that can support a standalone multi-billion public company or as a major acquisition by big pharma down the road.

However, as we have noted above there is also the chance that Nemucore fails to obtain FDA approval, in which case the asset would be worth little. For these reasons, we think Nemucore is an investment that warrants investment, but the amount invested should reflect the risk-reward curve we have called out. A Boston College Eagle for life, on a mission to democratize startup investing for all people at KingsCrowd, with a passion for Fintech, investing, social impact, doing well and doing good, and an avid runner, cyclist and writer.


Become part of the growing movement. Invest in Kingscrowd Today! Invest today. The Pharmaceutical Target Nemucore Medical Innovations is developing an Aurora kinase precision pharmaceutical called NMI in scientific communities for a blood cancer called acute myeloid leukemia AML that is paired with a companion diagnostic. View Chris lustrino's deals.

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Valuation Cap 20M. Number of Investors A Quest Diagnostics Inc. Insurers see ordering of unnecessary lab tests by doctors in a fee-for-service system that emphasizes volume of care delivered as in dire need of reform. In the future, lab tests will increasingly be subject to quality and outcome measures via various value-based care models.

UnitedHealth Signs Value-Based Lab Deals With Quest Diagnostics And LabCorp

The lab deal further escalates the trend away from volume of care delivered in a fee-for-service system to getting patient care in the right place, in the right amount and at the right time. UnitedHealth and its rivals including Aetna, Anthem, Cigna and Humana are shifting rapidly to value-based models with more than half of their reimbursements to doctors paid based on outcomes and quality measures.

That means more reimbursement to doctors will come via bundled payments, accountable care organizations ACOs , medical home models and pay-for-performance contracts.